
Mometasone furoate
CAS No. 83919-23-7
Mometasone furoate( SCH 32088 )
Catalog No. M16116 CAS No. 83919-23-7
Mometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
25MG | 35 | In Stock |
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50MG | 43 | In Stock |
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100MG | 79 | In Stock |
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200MG | 97 | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameMometasone furoate
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NoteResearch use only, not for human use.
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Brief DescriptionMometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.
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DescriptionMometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways. Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis), allergic rhinitis (such as hay fever), asthma for patients unresponsive to less potent corticosteroids, and penile phimosis. In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone.(In Vitro):Mometasone furoate binds to a glucocorticoid receptor causes conformational changes in the receptor, separation from chaperones, and the receptor moves to the nucleus.Mometasone furoate (0.1-10 μM; 2h before LPS stimulation) strongly inhibits LPS-stimulated nitrite production in a concentration-dependent manner in J774 macrophages, The IC50 value is 0.00024 μM for Mometasone?furoate in J774 cells.Mometasone furoate (0.1-10 μM; 2h before LPS stimulation) is more potent than DEX, it significantly inhibits iNOS expression at a 0.01 μM concentration whereas Dex became active at 0.1 μM. Additionally, the inhibition of cox-2 protein expression at 0.01 μM is 79% for Mometasone?furoate and 39% for Dex.
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In Vitro——
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In Vivo——
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SynonymsSCH 32088
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PathwayEndocrinology/Hormones
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TargetGR
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RecptorGlucocorticoid Receptor
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number83919-23-7
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Formula Weight521.43
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Molecular FormulaC27H30Cl2O6
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Purity>98% (HPLC)
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SolubilityDMSO: 6 mg/mL (11.5 mM)
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SMILESO=C(C1=CC=CO1)O[C@]2(C(CCl)=O)[C@H](C)C[C@@]3([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4(Cl)[C@@H](O)C[C@]23C)=O
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Chemical Name(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Isogai M, et al. J Steroid Biochem Mol Biol. 1993 Feb;44(2):141-5.
molnova catalog



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